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Article

Using high-density DNA methylation arrays to profile copy number alterations.

Genome biology - 3 Feb 2014

Feber Andrew, Guilhamon Paul, Lechner Matthias, Fenton Tim, Wilson Gareth A, Thirlwell Christina, Morris Tiffany J, Flanagan Adrienne M, Teschendorff Andrew E, Kelly John D, Beck Stephan

Abstract excerpt

The integration of genomic and epigenomic data is an increasingly popular approach for studying the complex mechanisms driving cancer development. We have developed a method for evaluating both methylation and copy number from high-density DNA methylation arrays. Comparing copy number data from Infinium HumanMethylation450 BeadChips and SNP arrays, we demonstrate that Infinium arrays detect copy number...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24490765
DOI: 10.1186/gb-2014-15-2-r30
PMCID: PMC4054098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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