Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alzheimer’s-Related Peptide Amyloid-β Plays a Conserved Role in Angiogenesis

9 Jul 2012

Abstract excerpt

Alzheimer's disease research has been at an impasse in recent years with lingering questions about the involvement of Amyloid-β (Aβ). Early versions of the amyloid hypothesis considered Aβ something of an undesirable byproduct of APP processing that wreaks havoc on the human neocortex, yet evolutionary conservation--over three hundred million years--indicates this peptide plays an important biological role in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Epigenetics and DNA Methylation
Share to Nuclear Receptors and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22792182
DOI: 10.1371/journal.pone.0039598

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alzheimer’s-Related Peptide Amyloid-β Plays a Conserved Role in AngiogenesisPMID 22792182Read ↗

Anti-angiogenic activity of the mutant Dutch A(beta) peptide on human brain microvascular endothelial cells.Semantic proximity Read ↗

Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesisSemantic proximity Read ↗

Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide.Semantic proximity Read ↗

Dysplasia of cortical capillaries as the origin of Alzheimer’s disease: experimental evidence from APP/PS1Semantic proximity Read ↗

Amyloid beta peptides (Aβ) from Alzheimer’s disease neuronal secretome induce endothelial activation in a human cerebral microvessel modelSemantic proximity Read ↗

AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch SignalingSemantic proximity Read ↗

Aβ peptide and fibrinogen weave a web of destruction in cerebral amyloid angiopathy.Semantic proximity Read ↗

Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changesSemantic proximity Read ↗

Impaired angiogenesis in a transgenic mouse model of cerebral amyloidosisSemantic proximity Read ↗

Soluble epoxide hydrolase in Alzheimer’s disease drives neurovascular dysfunctionSemantic proximity Read ↗

Linking cross-species trajectories of cerebrovascular remodeling in aging and Alzheimer’s disease to brain vessel transcriptomeSemantic proximity Read ↗

Endothelial Senescence and Its Impact on Angiogenesis in Alzheimer’s DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.