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Article

Anti-angiogenic activity of the mutant Dutch A(beta) peptide on human brain microvascular endothelial cells.

Brain research. Molecular brain research - 20 May 2005

Paris Daniel, Ait-Ghezala Ghania, Mathura Venkatarajan S, Patel Nikunj, Quadros Amita, Laporte Vincent, Mullan Mike

Abstract excerpt

Cerebral amyloid angiopathy is a common pathological feature of patients with Alzheimer's disease (AD) and it is also the hallmark of individuals with a rare autosomal dominant disorder known as hereditary cerebral hemorrhage with amyloidosis-Dutch type. We have shown previously that wild type A(beta) peptides are anti-angiogenic both in vitro and in vivo and could contribute to the compromised cerebrovascular...

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Identifiers

PMID: 15893605
DOI: 10.1016/j.molbrainres.2005.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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