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Endothelial Senescence and Its Impact on Angiogenesis in Alzheimer’s Disease

12 Jul 2023

Abstract excerpt

Endothelial cells are constantly exposed to environmental stress factors that, above a certain threshold, trigger cellular senescence and apoptosis. The altered vascular function affects new vessel formation and endothelial fitness, contributing to the progression of age-related diseases. This narrative review highlights the complex interplay between senescence, oxidative stress, extracellular vesicles, and the...

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PMID: 37511104
DOI: 10.3390/ijms241411344

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