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Article

Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Mar 2008

Patel Nikunj S, Quadros Amita, Brem Steven, Wotoczek-Obadia Marguerite, Mathura Venkatarajan S, Laporte Vincent, Mullan Michael, Paris Daniel

Abstract excerpt

Abeta peptides are the major constituents of senile plaques and cerebrovascular deposits in the brains of patients with Alzheimer's disease. We have shown previously that Abeta1-40 and Abeta1-42 peptides are potently anti-angiogenic both in vitro and in vivo. The current study characterizes important sequences within the Abeta peptide that are required to exert its anti-angiogenic activity. We have used human...

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PMID: 18266117
DOI: 10.1080/13506120701814723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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