Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Derivation of neural stem cells from an animal model of psychiatric disease.

Translational psychiatry - 5 Nov 2013

de Koning A, Walton N M, Shin R, Chen Q, Miyake S, Tajinda K, Gross A K, Kogan J H, Heusner C L, Tamura K, Matsumoto M

Abstract excerpt

Several psychiatric and neurological diseases are associated with altered hippocampal neurogenesis, suggesting differing neural stem cell (NSC) function may play a critical role in these diseases. To investigate the role of resident NSCs in a murine model of psychiatric disease, we sought to isolate and characterize NSCs from alpha-calcium-/calmodulin-dependent protein kinase II heterozygous knockout (CaMK2α-hKO)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Calcium-Calmodulin-Dependent Protein Kinase Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dentate Gyrus

Share to Hippocampus

Share to Neural Stem Cells

Share to Neurogenesis

Share to Neurons

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 24193728
DOI: 10.1038/tp.2013.96
PMCID: PMC3849963

Genes

MAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Derivation of neural stem cells from an animal model of psychiatric disease.PMID 24193728Read ↗

Detection of an immature dentate gyrus feature in human schizophrenia/bipolar patients.Semantic proximity Read ↗

Intrauterine environment-genome interaction and children's development (4): Brain-behavior phenotypying of genetically-engineered mice using a comprehensive behavioral test battery on research of neuropsychiatric disorders.Semantic proximity Read ↗

Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia.Semantic proximity Read ↗

Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain.Semantic proximity Read ↗

Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation.Semantic proximity Read ↗

Dysregulation of astrocyte extracellular signaling in Costello syndrome.Semantic proximity Read ↗

Neurosphere culture derived from aged hippocampal dentate gyrusSemantic proximity Read ↗

Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants.Semantic proximity Read ↗

Glial-Restricted Precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablationSemantic proximity Read ↗

Impaired neural differentiation of induced pluripotent stem cells generated from a mouse model of Sandhoff disease.Semantic proximity Read ↗

Enriched environment ameliorates adult hippocampal neurogenesis deficits in Tcf4 haploinsufficient miceSemantic proximity Read ↗

Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca2+ entry and accelerated differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.