Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immature-like molecular expression patterns in the hippocampus of a mouse model of dementia with Lewy body-linked mutant β-synuclein.

Molecular brain - 6 Jul 2018

Hagihara Hideo, Fujita Masayo, Umemori Juzoh, Hashimoto Makoto, Miyakawa Tsuyoshi

Abstract excerpt

AIM: Maturation abnormalities of the brain cells have been suggested in several neuropsychiatric disorders, including schizophrenia, bipolar disorder, autism spectrum disorders, and epilepsy. In this study, we examined the expression patterns of neuronal maturation markers in the brain of a mouse model of dementia with Lewy body-linked mutant β-synuclein (βS), especially in the hippocampus, to explore whether...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dementia
Share to Dentate Gyrus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Hippocampus

Share to Lewy Bodies

Share to Mice, Transgenic

Share to Mutation

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 29976232
DOI: 10.1186/s13041-018-0378-3
PMCID: PMC6034225

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immature-like molecular expression patterns in the hippocampus of a mouse model of dementia with Lewy body-linked mutant β-synuclein.PMID 29976232Read ↗

Alpha-Synuclein Pathology Coincides With Increased Number of Early Stage Neural Progenitors in the Adult HippocampusSemantic proximity Read ↗

Transcriptional Dysregulation in the Hippocampus of a murine model for Parkinson’s Disease Cognition Impairment is Driven by Sex, Age, and Alpha-synuclein overexpressionSemantic proximity Read ↗

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse modelSemantic proximity Read ↗

Detection of an immature dentate gyrus feature in human schizophrenia/bipolar patients.Semantic proximity Read ↗

Alzheimer disease-like cellular phenotype of newborn granule neurons can be reversed in GSK-3β-overexpressing mice.Semantic proximity Read ↗

Oligodendrocyte generation and maturation in the hippocampus may be a target of fluoxetine for delaying cognitive dysfunction during early Alzheimer’s diseaseSemantic proximity Read ↗

Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice.Semantic proximity Read ↗

Learning and Memory in S100-β Transgenic Mice: An Analysis of Impaired and Preserved FunctionSemantic proximity Read ↗

A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brainSemantic proximity Read ↗

Human brain S100β and S100β mRNA expression increases with age: Pathogenic implications for Alzheimer's diseaseSemantic proximity Read ↗

Early Impairments of Hippocampal Neurogenesis in 5xFAD Mouse Model of Alzheimer’s Disease Are Associated with Altered Expression of SOXB Transcription FactorsSemantic proximity Read ↗

Possible Role of Amyloidogenic Evolvability in Dementia with Lewy Bodies: Insights from Transgenic Mice Expressing P123H β-Synuclein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.