Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heartworms, macrocyclic lactones, and the specter of resistance to prevention in the United States

9 Jul 2012

Abstract excerpt

In order to provide a background to current concerns relative to the possible resistance of heartworms to macrocyclic lactones, this review summarizes various studies in which lack of efficacies (LOEs) have been observed in dogs on macrocyclic lactone preventives relative to the United States of America. Some of these studies have been published in the peer-reviewed literature, others have appeared in various...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Helminth infection and control
Share to Parasite Biology and Host Interactions
Share to Parasitic Diseases Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22776618
DOI: 10.1186/1756-3305-5-138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heartworms, macrocyclic lactones, and the specter of resistance to prevention in the United StatesPMID 22776618Read ↗

Macrocyclic lactone resistance in Dirofilaria immitis: risks for prevention of heartworm diseaseSemantic proximity Read ↗

Concern for <em>Dirofilaria immitis</em> and Macrocyclic Lactone Loss of Efficacy: Current Situation in the USA and Europe, and Future ScenariosSemantic proximity Read ↗

Macrocyclic lactone resistance in Dirofilaria immitis: Failure of heartworm preventives and investigation of genetic markers for resistance.Semantic proximity Read ↗

First case of macrocyclic lactone-resistant Dirofilaria immitis in Europe - Cause for concern.Semantic proximity Read ↗

Evidence for Macrocyclic Lactone Anthelmintic Resistance in Dirofilaria immitisSemantic proximity Read ↗

Laboratory assays reveal diverse phenotypes among microfilariae of Dirofilaria immitis isolates with known macrocyclic lactone susceptibility status.Semantic proximity Read ↗

Surveillance of single nucleotide polymorphisms correlated to macrocyclic lactone resistance in Dirofilaria immitis from client-owned dogs across the United States.Semantic proximity Read ↗

Macrocyclic lactone resistance in Dirofilaria immitisSemantic proximity Read ↗

Genetic profiles of ten Dirofilaria immitis isolates susceptible or resistant to macrocyclic lactone heartworm preventives.Semantic proximity Read ↗

Correlation between loss of efficacy of macrocyclic lactone heartworm anthelmintics and P-glycoprotein genotype.Semantic proximity Read ↗

Investigating Dirofilaria immitis isolates infecting domestic canines and their susceptibility/resistance patterns to macrocyclic lactones in the northern region of the Mississippi Delta area (southeast Missouri).Semantic proximity Read ↗

Clinical validation of molecular markers of macrocyclic lactone resistance in Dirofilaria immitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.