Article
B cell tolerance and positive selection in lupus.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2012
Eilat Dan, Wabl Matthias
Abstract excerpt
Systemic lupus erythematosus is considered a prototype of systemic autoimmune diseases; however, despite considerable advances in recent years in the understanding of basic mechanisms in immunology, little progress has been made in elucidating the etiology and pathogenesis of this disease. This even holds for inbred mice, such as the lupus-prone New Zealand Black/New Zealand White F(1) mice, which are all...
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