Article
Vascular endothelial growth factor polymorphisms increase the risk of developing Graves' disease.
International immunopharmacology - 1 Oct 2012
Vural Pervin, Baki Merve, Doğru-Abbasoğlu Semra, Özderya Ayşenur, Karadağ Berrin, Uysal Müjdat
Abstract excerpt
BACKGROUND: Graves' disease (GD) is a consequence of genetic and environmental factors. Vascular endothelial growth factor (VEGF) is a strong angiogenic and mitogenic factor, which plays a key role in lymphocyte infiltration, and hypervascularization in the thyroid gland of patients with GD. AIM: The aim of this study is to investigate the relationship between GD and A-2578C, T-460C and G+405C single nucleotide...
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