Article
Vascular endothelial growth factor G+405C polymorphism may contribute to the risk of developing papillary thyroid carcinoma.
Journal of clinical laboratory analysis - 1 Nov 2017
Bingül İlknur, Vural Pervin, Doğru-Abbasoğlu Semra, Çil Esra, Uysal Müjdat
Abstract excerpt
BACKGROUND: Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. Vascular endothelial growth factor (VEGF) is a mediator implicated with cell proliferation, differentiation and migration, and monocyte/macrophage chemotaxis. In present study, we aimed to investigate the relationship between VEGF gene polymorphisms (G+405C, T-460C, and A-2578C) and PTC susceptibility. METHODS: DNA was isolated...
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