Polygenic Prediction of Recurrent Events After Early-Onset Myocardial Infarction.

doi:10.1161/CIRCGEN.124.004687

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Article

Polygenic Prediction of Recurrent Events After Early-Onset Myocardial Infarction.

Circulation. Genomic and precision medicine - 1 Dec 2024

Ardissino Maddalena, Paraboschi Elvezia Maria, Lambert Samuel A, Kim Lois G, Kelemen Martin, Maglietta Giuseppe, Crocamo Antonio, Magnani Giulia, Bricoli Serena, Vignali Luigi, Niccoli Giampaolo, Tubaro Marco, Pastika Libor, Sau Arunashis, Ng Fu Siong, de Marvao Antonio, Honigberg Michael C, Natarajan Pradeep, Nelson Adam J, Inouye Michael, Di Angelantonio Emanuele, Asselta Rosanna, Ardissino Diego, Butterworth Adam S

Abstract excerpt

BACKGROUND: Myocardial infarction (MI) is a complex disease caused by both lifestyle and genetic factors. This study aims to investigate the predictive value of genetic risk, in addition to traditional cardiovascular risk factors, for recurrent events following early-onset MI. METHODS: The Italian Genetic Study of Early-Onset Myocardial Infarction is a cohort study enrolling patients with MI before 45 years....

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Identifiers

PMID: 39611259
DOI: 10.1161/CIRCGEN.124.004687
PMCID: PMC11651354

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