Article
Association of variation in the chromosome 9p21 locus with myocardial infarction versus chronic coronary artery disease.
Circulation. Cardiovascular genetics - 1 Dec 2008
Horne Benjamin D, Carlquist John F, Muhlestein Joseph B, Bair Tami L, Anderson Jeffrey L
Abstract excerpt
BACKGROUND: A chromosome 9p21 locus is associated with coronary heart disease in 25 independent populations, but multiple clinically distinct phenotypes have been evaluated. Using angiographic coronary artery disease (CAD) phenotyping, this study evaluated whether 9p21 single-nucleotide polymorphisms predict ischemic events (eg, myocardial infarction [MI]) among CAD patients. METHODS AND RESULTS: Patients...
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