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Article

Variations in the epigenetic regulation of lineage-specific genes among human pluripotent stem cell lines.

Biochemical and biophysical research communications - 27 Jul 2012

Kim Hyemin, Kim Dongkyu, Jang Mi-Jin, Han Yong-Mahn

Abstract excerpt

Pluripotent stem cells (PSCs) have unique transcriptional regulatory networks and epigenetic states that are involved in maintaining pluripotency. In this study, the transcriptional levels and histone modifications of lineage-specific genes were compared for human ESC (hESC) lines and human induced pluripotent stem cell (hiPSC) lines. Expression of the pluripotency marker genes, OCT4, SOX2, and NANOG, was largely...

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Source

Identifiers

PMID: 22766502
DOI: 10.1016/j.bbrc.2012.06.122

Genes

MYC
NANOG
SOX17
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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