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Article

Common stemness regulators of embryonic and cancer stem cells

1 Jan 2015

Abstract excerpt

Pluripotency of embryonic stem cells (ESCs) and induced pluripotent stem cells is regulated by a well characterized gene transcription circuitry. The circuitry is assembled by ESC specific transcription factors, signal transducing molecules and epigenetic regulators. Growing understanding of stem-like cells, albeit of more complex phenotypes, present in tumors (cancer stem cells), provides a common conceptual and...

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PMID: 26516408
DOI: 10.4252/wjsc.v7.i9.1150

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