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Article

Parkin is the most common causative gene in a cohort of mainland Chinese patients with sporadic early-onset Parkinson's disease.

Brain and behavior - 1 Sept 2020

Jiang Yanyan, Yu Meng, Chen Jing, Zhou Hong, Sun Wei, Sun Yunchuang, Li Fan, Wei Luhua, Pinkhardt Elmar H, Zhang Lin, Yuan Yun, Wang Zhaoxia

Abstract excerpt

INTRODUCTION: Genetic mutations associated with early-onset Parkinson's disease (EOPD) vary widely among different ethnicities. We detected the genes associated with EOPD in a Chinese cohort using next-generation sequencing (NGS) combined with multiplex ligation-dependent probe amplification (MLPA) and analyzed the phenotypic characteristics of the mutation carriers. METHODS: Cohort of 23 sporadic EOPD patients...

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Identifiers

PMID: 32677319
DOI: 10.1002/brb3.1765
PMCID: PMC7507393

Genes

VPS13C

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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