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Article

Genetic variants in Ecuadorian families: unraveling the complexity of non-syndromic cleft lip and palate a case series.

BMC oral health - 4 Mar 2026

Luna-Chonata Darwin, Guaillas-Japon Auki, Almeida Nicolás, Romero Vanessa I, Arias-Almeida Benjamin, Palacios Iván

Abstract excerpt

BACKGROUND: Cleft lip with or without cleft palate (CL ± P) is a common congenital anomaly with complex genetic origins. CASE PRESENTATION: This study presents a genetic case series of three Ecuadorian families with non-syndromic cleft lip and/or palate analyzed using whole-exome sequencing (WES). We identified rare or novel variants in genes with established or emerging roles in craniofacial development....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41781901
DOI: 10.1186/s12903-026-07796-8
PMCID: PMC13067646

Genes

KIF7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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