Article
Triazole resistance surveillance in Aspergillus fumigatus.
Medical mycology - 1 Apr 2018
Resendiz Sharpe Agustin, Lagrou Katrien, Meis Jacques F, Chowdhary Anuradha, Lockhart Shawn R, Verweij Paul E
Abstract excerpt
Triazole resistance is an increasing concern in the opportunistic mold Aspergillus fumigatus. Resistance can develop through exposure to azole compounds during azole therapy or in the environment. Resistance mutations are commonly found in the Cyp51A-gene, although other known and unknown resistance mechanisms may be present. Surveillance studies show triazole resistance in six continents, although the presence...
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