Article
Concomitant occurrence of itraconazole-resistant and -susceptible strains of Aspergillus fumigatus in routine cultures.
The Journal of antimicrobial chemotherapy - 1 Feb 2015
Ahmad Suhail, Joseph Leena, Hagen Ferry, Meis Jacques F, Khan Ziauddin
Abstract excerpt
OBJECTIVES: Resistance to triazoles in Aspergillus fumigatus has emerged in several countries and is usually mediated by mutations in the cyp51A gene. We determined the presence of both itraconazole-susceptible and -resistant A. fumigatus in routine cultures isolated from environmental and clinical samples. METHODS: A total of 50 environmental and 16 clinical A. fumigatus isolates obtained from single colonies...
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