Article
SIRPα interacts with nephrin at the podocyte slit diaphragm.
The FEBS journal - 1 Sept 2012
Kajiho Yuko, Harita Yutaka, Kurihara Hidetake, Horita Shigeru, Matsunaga Atsuko, Tsurumi Haruko, Kanda Shoichiro, Sugawara Noriko, Miura Kenichiro, Sekine Takashi, Hattori Seisuke, Hattori Motoshi, Igarashi Takashi
Abstract excerpt
The slit diaphragm (SD) is an intercellular junction between renal glomerular epithelial cells (podocytes) that is essential for permselectivity in glomerular ultrafiltration. The SD components, nephrin and Neph1, assemble a signaling complex in a tyrosine phosphorylation dependent manner, and re...
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