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An update: the role of Nephrin inside and outside the kidney

29 Apr 2015

Abstract excerpt

Nephrin is a key molecule in podocytes to maintain normal slit diaphragm structure. Nephin interacts with many other podocyte and slit diaphragm protein and also mediates important cell signaling pathways in podocytes. Loss of nephrin during the development leads to the congenital nephrotic syndrome in children. Reduction of nephrin expression is often observed in adult kidney diseases including diabetic...

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PMID: 25921941
DOI: 10.1007/s11427-015-4844-1

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