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Article

Role of nephrin in cell junction formation in human nephrogenesis.

The American journal of pathology - 1 Dec 2000

Ruotsalainen V, Patrakka J, Tissari P, Reponen P, Hess M, Kestilä M, Holmberg C, Salonen R, Heikinheimo M, Wartiovaara J, Tryggvason K, Jalanko H

Abstract excerpt

Nephrin is a cell adhesion protein located at the slit diaphragm area of glomerular podocytes. Mutations in nephrin-coding gene (NPHS1) cause congenital nephrotic syndrome (NPHS1). We studied the developmental expression of nephrin, ZO-1 and P-cadherin in normal fetal kidneys and in NPHS1 kidneys...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11106563
DOI: 10.1016/S0002-9440(10)64829-8
PMCID: PMC1885750

Genes

NPHS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11106563-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Role of nephrin in cell junction formation in human nephrogenesis.PMID 11106563Read ↗

Nephrin is specifically located at the slit diaphragm of glomerular podocytes.Semantic proximity Read ↗

An update: the role of Nephrin inside and outside the kidneySemantic proximity Read ↗

Nephrin TRAP mice lack slit diaphragms and show fibrotic glomeruli and cystic tubular lesions.Semantic proximity Read ↗

Genetic kidney diseases disclose the pathogenesis of proteinuria.Semantic proximity Read ↗

Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and BeyondSemantic proximity Read ↗

Tissue expression of nephrin in human and pig.Semantic proximity Read ↗

Nephrin Localizes at the Podocyte Filtration Slit Area and Is Characteristically Spliced in the Human KidneySemantic proximity Read ↗

SIRPα interacts with nephrin at the podocyte slit diaphragm.Semantic proximity Read ↗

Glomerular sclerosis in kidneys with congenital nephrotic syndrome (NPHS1).Semantic proximity Read ↗

Revisiting nephrin signaling and its specialized effects on the uniquely adaptable podocyteSemantic proximity Read ↗

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