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Article

Distribution of the major cytochrome P450 (CYP) 2C9 genetic variants in a Saudi population.

Basic & clinical pharmacology & toxicology - 1 Aug 2011

Mirghani Rajaa A, Chowdhary Gulnaz, Elghazali Gehad

Abstract excerpt

Cytochrome P450 (CYP) 2C9 is responsible for the metabolism of a number of widely used drugs such as oral anticoagulants, oral antidiabetics and non-steroidal anti-inflammatory drugs. The CYP2C9 is a genetically polymorphic enzyme. The most common allele is CYP2C9*1, while CYP2C9*2 and CYP2C9*3 are the less-frequent variants. The activity of the enzyme encoded by either CYP2C9 *2 or *3 variant is lower compared...

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PMID: 21371265
DOI: 10.1111/j.1742-7843.2011.00692.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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