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Prodromal Metabolic Phenotype in MCI Cybrids: Implications for Alzheimer’s Disease

1 Feb 2013

Abstract excerpt

Mild cognitive impairment (MCI) is considered a nosological entity or a translational state between normal aging and sporadic Alzheimer's disease (AD). From brain tissue to peripheral blood samples, it is evident that the early markers of metabolic dysfunction observed in AD have also been found in MCI subjects. These observations obtained from MCI and AD subjects leave open the possibility that mitochondrial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22746213
DOI: 10.2174/1567205011310020008

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