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Mitochondria, mitochondrial DNA and Alzheimer's disease. What comes first?

Current Alzheimer research - 1 Oct 2008

Mancuso M, Orsucci D, Siciliano G, Murri L

Abstract excerpt

To date, the beta amyloid (Abeta) cascade hypothesis remains the main pathogenetic model of Alzheimer's disease (AD), but its role in the majority of sporadic AD cases is unclear. The mitochondria play central role in the bioenergetics of the cell and apoptotic cell death. In the past 20 years re...

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PMID: 18855587
DOI: 10.2174/156720508785908946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18855587-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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