Article
Secretion of slow-folding proteins by a Type 1 secretion system.
Bioengineered - 1 Jan 2000
Schwarz Christian K W, Lenders Michael H H, Smits Sander H J, Schmitt Lutz
Abstract excerpt
Protein production through dedicated secretion systems might offer an potential alternative to the conventional cytoplasmical expression. The application of Type 1 secretion systems of Gram-negative bacteria, however, where often not successful in the past for a wide range of proteins. Recently, two studies using the E. coli maltose binding protein (MalE) and the rat intestinal fatty acid binding protein (IFABP)...
Topics
- Animals
- Escherichia coli
- Escherichia coli Proteins
- Extracellular Space
- Fatty Acid-Binding Proteins
- Genetic Engineering
- Hemolysin Proteins
- Kinetics
- Mutation
- Periplasmic Binding Proteins
- Protein Folding