Article

Construction of a constitutively active type III secretion system for heterologous protein secretion

2022-02-25

Abstract excerpt

Proteins comprise a multibillion-dollar industry in enzymes and therapeutics, but bacterial protein production can be costly and inefficient. Proteins of interest (POIs) must be extracted from lysed cells, purified, and resolubilized. The Salmonella pathogenicity island 1 type III secretion system (T3SS) is a protein secretion complex in Salmonella that has been engineered to secrete heterologous proteins and ad...

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Literature Corpus work: efbf02bc-09ea-5098-bc57-b2e8c90a8812
DOI: 10.1101/2022.02.24.481905

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