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Article

Folding and aggregation of export-defective mutants of the maltose-binding protein.

Research in microbiology - 1 Sept 2002

Betton Jean-Michel, Phichith Denis, Hunke Sabine

Abstract excerpt

We previously characterized a defective-folding variant of the periplasmic maltose-binding protein, MalE31. To examine the alternative folding pathways open to the MalE31 precursor, we have analyzed the cellular fates of this aggregation-prone protein carrying altered signal sequences. Our results are most easily interpreted by a kinetic competition between exportation, folding, and degradation.

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Identifiers

PMID: 12405345
DOI: 10.1016/s0923-2508(02)01338-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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