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Article

Degradation versus aggregation of misfolded maltose-binding protein in the periplasm of Escherichia coli.

The Journal of biological chemistry - 10 Apr 1998

Betton J M, Sassoon N, Hofnung M, Laurent M

Abstract excerpt

The periplasmic fates of misfolded MalE31, a defective folding mutant of the maltose-binding protein, were determined by manipulating two cellular activities affecting the protein folding pathway in host cells: (i) the malEp promoter activity, which is controlled by the transcriptional activator MalT, and (ii) the DegP and Protease III periplasmic proteolytic activity. At a low level of expression, the...

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PMID: 9535871
DOI: 10.1074/jbc.273.15.8897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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