Article
Degradation versus aggregation of misfolded maltose-binding protein in the periplasm of Escherichia coli.
The Journal of biological chemistry - 10 Apr 1998
Betton J M, Sassoon N, Hofnung M, Laurent M
Abstract excerpt
The periplasmic fates of misfolded MalE31, a defective folding mutant of the maltose-binding protein, were determined by manipulating two cellular activities affecting the protein folding pathway in host cells: (i) the malEp promoter activity, which is controlled by the transcriptional activator...
Topics
- ATP-Binding Cassette Transporters
- Bacterial Proteins
- Carrier Proteins
- DNA-Binding Proteins
- Escherichia coli
- Escherichia coli Proteins
- Genotype
- Heat-Shock Proteins
- Kinetics
- Maltose
- Maltose-Binding Proteins
- Metalloendopeptidases
- Models, Chemical
- Monosaccharide Transport Proteins
- Mutagenesis
- Periplasm
- Periplasmic Binding Proteins
- Periplasmic Proteins