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Article

Clinical and genotypic correlates of mutation K65R in HIV-infected patients failing regimens not including tenofovir.

Journal of medical virology - 1 May 2006

Trotta Maria Paola, Bonfigli Sandro, Ceccherini-Silberstein Francesca, Bellagamba Rita, D'Arrigo Roberta, Soldani Fabio, Zaccarelli Mauro, Concetta Bellocchi Maria, Lorenzini Patrizia, Marconi Patrizia, Boumis Evangelo, Forbici Federica, Comandini Ubaldo Visco, Tozzi Valerio, Narciso Pasquale, Federico Perno Carlo, Antinori Andrea

Abstract excerpt

The mutation RT-K65R confers resistance to tenofovir (TDF). Although its prevalence is increasing with the use of this drug, clinical and genotypic correlates of K65R occurrence have yet to be fully identified. Clinical, virological and immunological and genotypic data of patients naïve for TDF who failed HAART regimens and underwent genotypic resistance test (GRT) during 1999-2003 were collected in a database...

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Identifiers

PMID: 16555278
DOI: 10.1002/jmv.20573

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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