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Article

Genome Editing with CompoZr Custom Zinc Finger Nucleases (ZFNs)

14 Jun 2012

Abstract excerpt

Genome editing is a powerful technique that can be used to elucidate gene function and the genetic basis of disease. Traditional gene editing methods such as chemical-based mutagenesis or random integration of DNA sequences confer indiscriminate genetic changes in an overall inefficient manner and require incorporation of undesirable synthetic sequences or use of aberrant culture conditions, potentially confusing...

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PMID: 22732945
DOI: 10.3791/3304

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