Article
A functional insertion/deletion polymorphism in the proximal promoter of CD3G is associated with susceptibility for hepatocellular carcinoma in Chinese population.
DNA and cell biology - 1 Sept 2012
Jiang Lingling, Xu Jingya, Ni Jianqiang, Gao Xueren, Zhu Zhansheng, Dong Dong, Wang Xiaoshu, Shi Chunhua, Tao Xiaoyang, Dong Wanli, Gao Yuzhen
Abstract excerpt
Hepatocellular carcinoma (HCC) represents the most common primary malignancy of the liver with a worldwide increasing incidence. Although the risk factors for HCC are well characterized, the molecular mechanisms responsible for malignant transformation of hepatocytes are not well understood. In this study, a case-control study including 291 HCC patients and 294 healthy controls was conducted to investigate the...
Topics
- Asian People
- CD3 Complex
- Carcinoma, Hepatocellular
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Hep G2 Cells
- Humans
- INDEL Mutation
- Liver Neoplasms
- Male
- Middle Aged
- Polymorphism, Genetic