Article
An indel polymorphism within pre-miR3131 confers risk for hepatocellular carcinoma.
Carcinogenesis - 1 Feb 2017
Wang Chaoqun, Li Lijuan, Yin Zhixia, Zhang Qing, Zhao Hua, Tao Ruiyang, Wang Shouyu, Hu Shuxiang, He Yan, Wang Dayong, Li Chengtao, Zhang Suhua, Xu Jiejie, Jiang Xinghong, Zhu Shaohua, Gao Yuzhen
Abstract excerpt
Polymorphisms in pre-miRNAs may affect its expression, then have effect on its target mRNAs and be associated with cancer susceptibility. In this study, we evaluated the association of an indel polymorphism rs57408770 in pre-miR-3131 with hepatocellular carcinoma (HCC) susceptibility in a Chinese population. The contribution of rs57408770 to HCC risk was investigated in two independent case-control sets (1051 HCC...
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