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Article

Application of a case-control study design to investigate genotypic signatures of HIV-1 transmission.

Retrovirology - 25 Jun 2012

Mota Talia M, Murray John M, Center Rob J, Purcell Damian F J, McCaw James M

Abstract excerpt

BACKGROUND: The characterization of HIV-1 transmission strains may inform the design of an effective vaccine. Shorter variable loops with fewer predicted glycosites have been suggested as signatures enriched in envelope sequences derived during acute HIV-1 infection. Specifically, a transmission-linked lack of glycosites within the V1 and V2 loops of gp120 provides greater access to an α4β7 binding motif, which...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22731404
DOI: 10.1186/1742-4690-9-54
PMCID: PMC3419081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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