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Article

Mycobacterium paratuberculosis is recognized by Toll-like receptors and NOD2.

Journal of leukocyte biology - 1 Oct 2007

Ferwerda Gerben, Kullberg Bart Jan, de Jong Dirk J, Girardin Stephen E, Langenberg Dennis M L, van Crevel Reinout, Ottenhoff Tom H M, Van der Meer Jos W M, Netea Mihai G

Abstract excerpt

Mycobacterium paratuberculosis has been suggested to be involved in the pathogenesis of Crohn's disease (CD). The importance of microorganisms in CD is supported by the association of CD with mutations in the intracellular pathogen recognition receptor (PRR) nucleotide-binding oligomerization domain 2 (NOD2). The aim of this study is to investigate the PRR involved in the recognition of M. paratuberculosis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17652449
DOI: 10.1189/jlb.0307147

Genes

NOD2
TLR2
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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