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Article

RING finger palmitoylation of the endoplasmic reticulum Gp78 E3 ubiquitin ligase.

FEBS letters - 30 Jul 2012

Fairbank Maria, Huang Kun, El-Husseini Alaa, Nabi Ivan R

Abstract excerpt

Gp78 is an E3 ubiquitin ligase within the endoplasmic reticulum-associated degradation pathway. We show that Flag-tagged gp78 undergoes sulfhydryl cysteine palmitoylation (S-palmitoylation) within the RING finger motif, responsible for its ubiquitin ligase activity. Screening of 19 palmitoyl acyl transferases (PATs) identified five that increased gp78 RING finger palmitoylation. Endoplasmic reticulum...

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Identifiers

PMID: 22728137
DOI: 10.1016/j.febslet.2012.06.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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