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Article

Palmitoylation landscapes across human cancers reveal a role of palmitoylation in tumorigenesis

17 Nov 2023

Abstract excerpt

BACKGROUND: Protein palmitoylation, which is catalyzed by palmitoyl-transferase and de-palmitoyl-transferase, plays a crucial role in various biological processes. However, the landscape and dynamics of protein palmitoylation in human cancers are not well understood. METHODS: We utilized 23 palmitoyl-acyltransferases and seven de-palmitoyl-acyltransferases as palmitoylation-related genes for protein...

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PMID: 37978524
DOI: 10.1186/s12967-023-04611-8

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