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The uptake of avermectins in <i>Caenorhabditis elegans</i> is dependent on Intra-Flagellar Transport and other protein trafficking pathways

2021-10-22

Abstract excerpt

Parasitic nematodes are globally important and place a heavy disease burden on infected humans, crops and livestock, while commonly administered anthelmintics used for treatment are being rendered ineffective by increasing levels of resistance. Although the modes of action and resistance mechanisms caused by detoxification and target site insensitivity for these compounds is well documented, the mechanisms for upt...

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Literature Corpus work
273acbf8-0cf4-52e6-a3f5-6c5156e2ddfe
DOI
10.1101/2021.10.22.465401
Open publication

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The uptake of avermectins in <i>Caenorhabditis elegans</i> is dependent on Intra-Flagellar Transport and other protein trafficking pathwaysDOI 10.1101/2021.10.22.465401
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