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Article

Transient sequestration of TORC1 into stress granules during heat stress.

Molecular cell - 27 Jul 2012

Takahara Terunao, Maeda Tatsuya

Abstract excerpt

The target of rapamycin complex 1 (TORC1) is a central kinase that coordinates nutrient availability with eukaryotic cell growth. Although TORC1 signaling is repressed by various stresses in yeast, the underlying mechanisms remain elusive. Here we report that TORC1 signaling upon heat stress is regulated by stress granules (SGs), which are cytoplasmic foci formed under certain stresses. Ectopic formation of SGs...

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Identifiers

PMID: 22727621
DOI: 10.1016/j.molcel.2012.05.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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