Article
Transient enriched housing before amyloidosis onset sustains cognitive improvement in Tg2576 mice.
Neurobiology of aging - 1 Jan 2013
Verret Laure, Krezymon Alice, Halley Hélène, Trouche Stéphanie, Zerwas Meike, Lazouret Marine, Lassalle Jean-Michel, Rampon Claire
Abstract excerpt
Levels of educational and occupational attainment, as components of cognitive reserve, may modify the relationship between the pathological hallmarks and cognition in Alzheimer's disease (AD). We examined whether exposure of a Tg2576 transgenic mouse model of AD to environmental enrichment (EE) at a specific period during the amyloidogenic process favored the establishment of a cognitive reserve. We found that...
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