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Article

Increased severity of acute graft versus host disease as a result of differential expression following a homozygous gene deletion.

International journal of immunogenetics - 1 Apr 2013

Jervis S, Collins P, Tate D, Foster L, Bowman V, Adhern C, Bloor A, Yin J, Wynn R, Poulton K

Abstract excerpt

Acute graft versus host disease (aGvHD) is a major cause of early morbidity post-haematopoietic stem cell transplantation with minor histocompatibility antigens being a contributing factor. One mHA encoded by the UDP glycosyltransferase 2 family polypeptide B17 (UGT2B17) gene has been shown to be immunogenic because of differential expression in the donor and recipient. We investigated the effects of a homozygous...

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Source

Identifiers

PMID: 22726315
DOI: 10.1111/j.1744-313X.2012.01138.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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