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Article

Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H.

Bioscience reports - 1 Oct 2012

Kim Ju Hee, Kang Sunghyun, Jung Suk-Kyeong, Yu Keum Ran, Chung Sang J, Chung Bong Hyun, Erikson Raymond L, Kim Bo Yeon, Kim Seung Jun

Abstract excerpt

RNase H (retroviral ribonuclease H) cleaves the phosphate backbone of the RNA template within an RNA/DNA hybrid to complete the synthesis of double-stranded viral DNA. In the present study we have determined the complete structure of the RNase H domain from XMRV (xenotropic murine leukaemia virus-related virus) RT (reverse transcriptase). The basic protrusion motif of the XMRV RNase H domain is folded as a short...

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Identifiers

PMID: 22724525
DOI: 10.1042/BSR20120028
PMCID: PMC3475449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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