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Article

Deregulation of Rab and Rab effector genes in bladder cancer.

PloS one - 1 Jan 2012

Ho Joel R, Chapeaublanc Elodie, Kirkwood Lisa, Nicolle Remy, Benhamou Simone, Lebret Thierry, Allory Yves, Southgate Jennifer, Radvanyi François, Goud Bruno

Abstract excerpt

Growing evidence indicates that Rab GTPases, key regulators of intracellular transport in eukaryotic cells, play an important role in cancer. We analysed the deregulation at the transcriptional level of the genes encoding Rab proteins and Rab-interacting proteins in bladder cancer pathogenesis, distinguishing between the two main progression pathways so far identified in bladder cancer: the Ta pathway...

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Source

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Identifiers

PMID: 22724020
DOI: 10.1371/journal.pone.0039469
PMCID: PMC3378553

Genes

FGFR3
MICAL2
MLPH
RAB20
RAB23
STXBP1
SYTL1
SYTL2
ZWINT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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