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Article

Expression of ral GTPases, their effectors, and activators in human bladder cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2007

Smith Steven Christopher, Oxford Gary, Baras Alexander S, Owens Charles, Havaleshko Dmytro, Brautigan David L, Safo Martin K, Theodorescu Dan

Abstract excerpt

PURPOSE: The Ral family of small G proteins has been implicated in tumorigenesis, invasion, and metastasis in in vitro and animal model systems; however, a systematic evaluation of the state of activation, mutation, or expression of these GTPases has not been reported in any tumor type. EXPERIMENTAL DESIGN: We determined the activation state of the RalA and RalB paralogs in 10 bladder cancer cell lines with...

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Source

Identifiers

PMID: 17606711
DOI: 10.1158/1078-0432.CCR-06-2419

Genes

HRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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