Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of RAB GTPases and Its Potential in Predicting Immunotherapy Response and Prognosis in Colorectal Cancer

28 Jan 2022

Abstract excerpt

Background: Colorectal cancer (CRC) is the third most common cancer worldwide, in which aberrant activation of the RAS signaling pathway appears frequently. RAB proteins (RABs) are the largest Ras small GTPases superfamily that regulates intracellular membrane trafficking pathways. The dysregulation of RABs have been found in various diseases including cancers. Compared with other members of Ras families, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Ferroptosis and cancer prognosis
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35154286
DOI: 10.3389/fgene.2022.828373

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of RAB GTPases and Its Potential in Predicting Immunotherapy Response and Prognosis in Colorectal CancerPMID 35154286Read ↗

RAB27A promotes the proliferation and invasion of colorectal cancer cellsSemantic proximity Read ↗

Functional implications of Rab27 GTPases in CancerSemantic proximity Read ↗

The interrelated roles of RAB family proteins in the advancement of neoplastic growthSemantic proximity Read ↗

Overexpression of RAB34 associates with tumor aggressiveness and immune infiltration in gliomaSemantic proximity Read ↗

Investigating the impact of Ras‐related protein RAB7A on colon adenocarcinoma behavior and its clinical significanceSemantic proximity Read ↗

Long Noncoding RNA MALAT1 Promotes Colorectal Cancer Progression by Acting as a ceRNA of miR‐508‐5p to Regulate RAB14 ExpressionSemantic proximity Read ↗

The relationship between microRNAs and Rab family GTPases in human cancersSemantic proximity Read ↗

Emerging roles for Rab family GTPases in human cancerSemantic proximity Read ↗

Comprehensive Analysis of Expression, Clinicopathological Association and Potential Prognostic Significance of RABs in Pancreatic CancerSemantic proximity Read ↗

Rho GTPase signaling in the development of colorectal cancerSemantic proximity Read ↗

Pan-cancer analysis reveals correlation between RAB3B expression and tumor heterogeneity, immune microenvironment, and prognosis in multiple cancers.Semantic proximity Read ↗

Identification of SRGAP2 as a Potential Oncogene and a Prognostic Biomarker in Hepatocellular Carcinoma Using Bioinformatics Analyses and Biological ExperimentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.