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Article

Identification of human fibroblast cell lines as a feeder layer for human corneal epithelial regeneration.

PloS one - 1 Jan 2012

Lu Rong, Bian Fang, Lin Jing, Su Zhitao, Qu Yangluowa, Pflugfelder Stephen C, Li De-Quan

Abstract excerpt

There is a great interest in using epithelium generated in vitro for tissue bioengineering. Mouse 3T3 fibroblasts have been used as a feeder layer to cultivate human epithelia including corneal epithelial cells for more than 3 decades. To avoid the use of xeno-components, we evaluated human fibro...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22723892
DOI: 10.1371/journal.pone.0038825
PMCID: PMC3377680

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22723892-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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