Article
Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer.
World journal of gastroenterology - 14 Jun 2012
Hezova Renata, Kovarikova Alena, Bienertova-Vasku Julie, Sachlova Milana, Redova Martina, Vasku Anna, Svoboda Marek, Radova Lenka, Kiss Igor, Vyzula Rostislav, Slaby Ondrej
Abstract excerpt
AIM: To investigate whether selected single nucleotide polymorphisms (SNPs) in miR-196a2, miR-27a and miR-146a genes are associated with sporadic colorectal cancer (CRC). METHODS: In order to investigate the effect of these SNPs in CRC, we performed a case-control study of 197 cases of sporadic CRC and 212 cancer-free controls originating from the Central-European Caucasian population using TaqMan Real-Time...
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