Article
A variant in microRNA-196a2 is not associated with susceptibility to and progression of colorectal cancer in Chinese.
Internal medicine journal - 1 Jun 2012
Chen H, Sun L-Y, Chen L-L, Zheng H-Q, Zhang Q-F
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs with regulatory functions as tumour suppressors and oncogenes. Although single nucleotide polymorphism (SNP) in miRNA regions have been reported to be rare and unlikely to be functionally important, recent evidence suggested that rs11614913 SNP in miR-196a2 was associated with the susceptibility of lung cancer, breast cancer, congenital heart disease and...
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