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Article

A genetic variant in miR-196a2 increased digestive system cancer risks: a meta-analysis of 15 case-control studies.

PloS one - 1 Jan 2012

Guo Jing, Jin Mingjuan, Zhang Mingwu, Chen Kun

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) negatively regulate the gene expression and act as tumor suppressors or oncogenes in oncogenesis. The association between single nucleotide polymorphism (SNP) in miR-196a2 rs11614913 and the susceptibility of digestive system cancers was inconsistent in previous studies. METHODOLOGY/PRINCIPAL FINDINGS: An updated meta-analysis based on 15 independent case-control studies consisting...

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Identifiers

PMID: 22291993
DOI: 10.1371/journal.pone.0030585
PMCID: PMC3265498

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Source receipt: pubmed, retrieved 7 Sept 2026.

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