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Article

Connexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2012

Lloyd Shane A, Lewis Gregory S, Zhang Yue, Paul Emmanuel M, Donahue Henry J

Abstract excerpt

Connexin 43 (Cx43) is the most abundant gap junction protein in bone and has been demonstrated as an integral component of skeletal homeostasis. In the present study, we sought to further refine the role of Cx43 in the response to mechanical unloading by subjecting skeletally mature mice with a b...

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Identifiers

PMID: 22714552
DOI: 10.1002/jbmr.1687
PMCID: PMC3683470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22714552-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Connexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading.PMID 22714552Read ↗

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